About us
GLOBAL DIAGNOSTICS LABS
A high-complexity CLIA and CAP-certified, service provider laboratory.
As a company, we have a clear focus to improve early detection of cervical disease and prevent cervical cancer with our Proofer 7 HPV-mRNA E6 and E7 Biomarker Test. We carefully focus on the needs of patients and users, by continued innovation and application of new technology.
At the end of 2023 Global Diagnostics Labs, LLC became a wholly owned subsidiary of Mel-Mont Medical, Inc
At Global Diagnostics Labs, we provide testing of cervical samples for HPV-mRNA E6 and E7 oncoproteins. HPV is the virus that is required for a woman to develop cervical cancer. Most women will have an HPV infection throughout their lifetime, but this is usually cleared by the body’s own immune system. It is the women who have infections of certain HPV types that are of concern, as these types are known to contribute towards cell changes, the first step on the road to cervical cancer.
This differs from an HPV DNA test that is available to some women in the national screening programme.
HPV DNA test
HPV mRNA test
- Detects the presence of HPV
- Tests for many HPV types, so a positive result could be any type of a long list
- Often doesn’t tell which type of HPV is present, just says positive or negative
HPV mRNA test
- Detects the overexpression of oncoproteins E6 and E7 from HPV mRNA
- Tests for 7 HPV types; 16, 18, 31, 33, 45, 52, and 58 as these cause the majority of cervical cancers
- Tells you which type of HPV is active, this is useful as some HPV types are more dangerous
Over the past 5 years we have been completing a project with Universitetssykehuset Nord-Norge to test over 100,000 samples to prove the ability of our test in helping women to avoid cervical cancer.
Many women have had precancerous abnormalities that required treatment found as a result of this study that were missed by the regular screening programme. The experiences of some of these women have recently been discussed in these NRK articles (read articles featuring Berit’s story or Tonje’s story).
Our test is designed to detect whether or not HPV is active in your cervix because this puts you at a known higher risk of developing precancerous lesions. Our test, Proofer 7 HPV-mRNA E6 and E7 Biomarker Test, detects the activity of 7 types of HPV; types 16, 18, 31, 33, 45, 52, and 58 as it is well documented that these are the leading causes of cervical cancer, even among women who have a “normal” smear result. Among young women HPV infections are common, so the HPV DNA test is not offered to these patients because there will be many positive results not associated with cancer and therefore a risk of over treatment. A positive HPV mRNA result, on the other hand, requires further investigation regardless of the age of the woman. Our focus is on finding the few women who require further examination from the many that do not.
Proofer 7 HPV-mRNA E6 and E7 Biomarker Test.
can be carried out on the same smear sample taken during a routine check-up with your clinician.
For any enquiries, or for more information, please use the form provided through the button.
